Laboratory Automation (2007): Our Biomek NX is used to purify RNA/DNA from samples and also to setup a range of assays in the lab. The precision of the 'robot' is greater than human pipetting and allows us to massively increase the throughput of sample processing.
DNA fragments being cut from an agarose gel exposed to UV.
A CFTR Western blot, to confirm protein production in cell culture.
A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
Schematic diagram of the large human airways.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).
Purifying mRNA from tissue samples.
A cake that only some of us got to enjoy!
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)
Pellets of DNA following precipitation.
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.
Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).
Proposed 3D model of the CFTR protein.
Large scale lentivirus production in suspension culture.