Laboratory Automation (2007): Our Biomek NX is used to purify RNA/DNA from samples and also to setup a range of assays in the lab. The precision of the 'robot' is greater than human pipetting and allows us to massively increase the throughput of sample processing.
Pellets of DNA following precipitation.
Large scale lentivirus production in suspension culture.
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)
Proposed 3D model of the CFTR protein.
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).
Purifying mRNA from tissue samples.
A cake that only some of us got to enjoy!
Schematic diagram of the large human airways.
DNA fragments being cut from an agarose gel exposed to UV.
A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).
A CFTR Western blot, to confirm protein production in cell culture.
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.